How to solve the brain puzzle in Baldur’s Gate 3

There are several ways to approach this puzzle. Fortunately, we have more nodes than necessary at our disposal, which allows us to have more options to create paths from one side to the other, so it is necessary to know how to solve the brain puzzle in Baldur's Gate 3 and be as attentive as possible with every step we take to do a good job and complete it.

A useful tactic is to pay attention to nodes that have only one entry. We can identify these nodes and create paths for them first, and then work on the remaining ones. With a controller, it's crucial to press L3 on PlayStation or LS on Xbox to activate the camera controls, making it easier to navigate the puzzle. Without them, we will not be able to move the nodes. However, on a PC it's easier, as we have the freedom to use WASD to move the camera, QE to rotate it, and the mouse to rearrange the puzzle nodes along our designated paths.

Once we have successfully linked all the nodes, a door will open at the back, which will give us the first part of our reward and it is the Blade of Oppressed Souls sword, a carving on the wall that provides information and a brain in a box known as Waking Mind. However, we must make sure we do not forget the brains behind it. The Blade of Oppressed Souls sword is also beneficial to those who wield long swords. While it may not have significant advantages, it does offer useful statistics such as:

It is a worthwhile acquisition if we need a new sword or want to take advantage of the additional psychic damage, it is the Awakening Mind that really arouses interest, likewise, using Waking Mind is crucial to progress in the game, in this sense, We will go to the farthest section of the laboratory and towards the opposite corner, where we will see a niche that houses a machine. This gadget allows us to place brains inside and communicate with them through a disembodied head. Larian Studios has really incorporated body horror elements into this segment.

The Awakened Mind, which we obtained from the room that opens after solving the brain puzzle in Baldur's Gate 3, contains the consciousness of a Githzerai. It is worth asking how they came to this state as their history is intriguing. In time, they will implore us to remove their brains and end their suffering using our brain worms or tadpole powers.

With this we get a blessing from the Githzerai before they die, this is an improvement that gives us advantage on intelligence saving throws. It will be useful if we are about to face formidable enemies like Mind Flayers. Similar to the benefit Gale provides with the puzzle in Balthazar's room in Moonrise, any extra help is valuable.

It is located on the Mind Flayer Colony map, within the Necrotic Laboratory area at coordinates X: 741, Y: -120. It is ideal to take a short break and rest before venturing into this area, things can get quite intense when we open the fleshy doors of the laboratory, we will have to face a multitude of challenges, such as a horde of zombies, various winged horrors and an incredibly enemy annoying, the Shepherd of Death, will be waiting for us.

Ideally, try to decimate it from afar while also using powerful area-of-effect enchantments, such as Ice Storm or Guardian of Faith, to contain the zombies; or have an individual, like Lae'zel, boldly charge into the rear lines and attempt to eliminate them quickly. We can also experiment with Shadowheart's Turn Undead ability or any other ability that is specifically effective against undead enemies. Once we have successfully endured the relentless assault, we will go to the back area where we will find a console on the left side, here we interact with it and the brain puzzle will be revealed to us. The voice tells us that we must connect the four unique components of your brain and they are Emotion, Reason, Speech and Memory to their corresponding receptors in order to progress.