All Items Tier List in Risk of Rain 2

By Ambar Jimenez | 2025-11-25 18:30:27
Survival in Risk of Rain 2 (RoR2) is a brutal equation where character skill meets item synergy. As the difficulty spirals out of control, the difference between a successful run and a painful death often boils down to a few key item pickups. While the game boasts a massive inventory of loot, focusing on items that offer consistent power and crucial utility is the bedrock of long-term survival.Instead of meticulously ranking every single drop, this guide focuses on the most valuable items across all rarities—the ones that define successful runs, trivialize bosses, and pull you back from the brink of disaster. By understanding these priorities, you can quickly identify the best loot drops for your survivor, minimize unnecessary grinding, and stack the synergies that break the game wide open.

Risk of Rain 2: All Items Tier List

The RoR2 Item Power Matrix: S, A, and B Tiers

The following tier list prioritizes items based on their overall impact across most survivors and general gameplay situations. Items are ranked strictly within their own rarity pool (e.g., a White S-Tier item is the best Common item, not necessarily equal to a Red S-Tier item).

White Items (Common): The Foundation of Every Run

White items are the bread and butter of your early game, and stacking the right ones immediately sets the stage for exponential scaling.

TierConsistently Powerful (S-Tier)Strong, More Situational (A-Tier)Solid, Not Run-Defining (B-Tier)
CommonLens-Maker’s Glasses (Crit chance), Soldier’s Syringe (Attack speed), Paul’s Goat Hoof (Movement speed), Topaz Brooch (Temporary barrier)Focus Crystal (Close-range damage), Crowbar (Full-health damage), Armor-Piercing Rounds (Boss damage), Tri-Tip Dagger (Bleed chance), Monster Tooth (Minor healing)Bundle of Fireworks, Rusted Key
  • Priority Focus: Stacking Lens-Maker’s Glasses to achieve 100% crit chance is the fastest way to multiply damage. Syringe and Hoof provide essential scaling in attack rate and mobility.

Green Items (Uncommon): Critical Synergy Pieces

Green items often provide the critical damage multipliers or utility effects that unlock powerful synergies.

TierConsistently Powerful (S-Tier)Strong, More Situational (A-Tier)Solid, Not Run-Defining (B-Tier)
UncommonUkulele (Chain lightning, AoE clear), Harvester’s Scythe (Consistent crit healing), Will-o’-the-Wisp (Massive explosion AoE on kill)Razorwire (Damage around player), AtG Missile Mk. 1 (Major single-target burst)
  • Priority Focus: Ukulele combined with high attack speed becomes unmatched crowd clear. Harvester’s Scythe provides much-needed sustain for crit-based builds.

Red Items (Legendary): Game-Defining Power

Legendary items fundamentally change the rules of the run, providing immense, late-game scaling potential.

TierConsistently Powerful (S-Tier)Strong, More Situational (A-Tier)Solid, Not Run-Defining (B-Tier)
LegendaryShaped Glass (Damage doubled, health halved—risky scaling), Kjaro’s Band (Fire AoE), Runald’s Band (Ice slow/damage), Sentient Meat Hook (Massive hook/pull utility and damage)Behemoth (Explosive hits), Rejuvenation Rack (Doubled healing), Backup Magazine (Extra equipment charge)
  • Priority Focus: The Bands are crucial damage multipliers, especially when combined with items that proc on-hit effects. Shaped Glass is the ultimate high-risk, high-reward power item.

Yellow Items (Boss): Boss-Slayer Synergy

Boss items are often the key to maximizing the effectiveness of other item stacks or granting unique, strategic advantages.

TierConsistently Powerful (S-Tier)Strong, More Situational (A-Tier)Solid, Not Run-Defining (B-Tier)
Boss57 Leaf Clover (Massive luck boost for proc chains), Queens Gland (Summon helper), Charged Perforator (High single-target lightning burst)H3AD-ST v2 (Mobility and dive damage)
  • Priority Focus: The 57 Leaf Clover is arguably the best item in the game, drastically increasing the chance of all proc effects (like Ukulele, Bands, and AtG Missile) activating, which leads to exponential damage scaling.

Blue Items (Lunar): Calculated Risk & Build Alteration

Lunar items are double-edged swords that can define unique builds but often come with a heavy cost. The S-Tier Lunar items are those where the benefit almost always outweighs the drawback.

TierConsistently Powerful (S-Tier)Strong, More Situational (A-Tier)Solid, Not Run-Defining (B-Tier)
LunarTranscendence (Turns all health into shield), Gesture of the Drowned (Automates Equipment), Spinel Tonic (Massive buff, with potential debuff)
  • Priority Focus: Transcendence is essential for late-game survival, eliminating slow healing in favor of fast-recharging shields. Gesture of the Drowned enables continuous use of powerful Equipment like the Gnarled Woodsprite for healing.

Lower Tier Items: Situational Utility and Extreme Risk

Many items fall into the C, D, and F tiers. These are often highly situational, niche, or actively harmful if not used with extreme caution or on specific survivors. While most players should avoid these until late in a run, they can enable unique, if unreliable, strategies.

  • Example: Purity (Lunar): Greatly reduces cooldowns but severely reduces your luck state, essentially shutting down all proc-based builds. Only useful for survivors relying solely on skill spam.
  • Example: Stone Flux Pauldron (Legendary): Doubles your damage but halves your movement speed. This is a run-killer for most survivors due to the huge hit to mobility.
RarityNiche, Conditional (C-Tier)Weak or Actively Harmful (D/F-Tier)
CommonBustling Fungus (Tier A/S for Engineer only)Bison Steak
UncommonGhor’s Tome (Monetary gain), Lost Seer’s Lenses (Instant kill chance)Old War Stealthkit, Hunter’s Harpoon
LegendaryWake of Vultures, Happiest Mask, Forgive Me Please, Resonance DiscStone Flux Pauldron, Frost Relic
BossIrradiant Pearl, Molten Perforator, PlanulaShared Design
LunarVisions of Heresy, Hooks of Heresy, Strides of Heresy, Encrusted KeyPurity, Brittle Crown, Benthic Bloom, Corpsebloom, Focus Converters, Eulogy Zero
DLC (Expansion)Breaching Fin, Warped EchoChronic Expansion, Sonorous Whispers

By focusing on the S-Tier and A-Tier items, especially the core multipliers like Lens-Maker’s Glasses, Soldier’s Syringe, Ukulele, and 57 Leaf Clover, you can quickly build the explosive synergies necessary to defeat the final boss and survive beyond the limits of the planet.

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