The first thing we must take into account before knowing how to use Preserved Medusa Head in Dragon's Dogma 2, is preserving the head for future use is essential, considering that at some point later, it can be useful due to the functionality of petrification that it possesses.
To use the preserved Medusa head, we must open our inventory and select the item, then we will choose the Equip option, we will see the Medusa head that appears on our character and is similar to a flashlight. Next, we will locate the monster we want to use the head, once in front of the monster, we will select the 'Brandish' command either by using the key combination (CTRL + R) or from our inventory. Then, our character will swing his head, freezing the nearest monster instead of us.
Here the main purpose of the preserved Medusa head is to petrify a monster during battle, highly useful in A Case of the Sculptor's Blockade, where Fulvius requests our help to fight a Gryphon while he is drawing. It should be noted that by using the Head of Medusa to petrify the Gryphon, Fulvius will have enough time to complete the task. This mission can be completed without the head of Medusa, however, with the head it is usually easier and faster. Similarly, the head can also be used in the mission The Guardian Gigantus where we can temporarily petrify the stone giant. A big bonus for getting the 'Gigantus, I barely knew you' achievement.
This is everything you need to know about How to use Preserved Medusa Head in Dragon's Dogma 2, so that you can take advantage of this advantage that the game offers and thus win more easily.