How to Unlock All Mutations in Grounded 2

By Daniel Hidalgo | 2025-08-03 12:07:06
In Grounded 2, Mutations are essential passive abilities that enhance your combat prowess, exploration efficiency, and survival skills. As you progress, unlocking these mutations will make you stronger against the backyard’s deadly creatures and environmental hazards. Each mutation has three tiers, with progressively stronger effects, and requires completing specific challenges to unlock.
This guide covers all 18 Mutations available in Grounded 2 (Early Access), categorized into Fighting Styles, Combat Abilities, Exploration, and Survival. We’ll also explain how to equip more mutations using Milk Molars and provide a breakdown of each mutation’s unlock requirements and effects.

All Mutations in Grounded 2 & How to Unlock Them

1. Fighting Styles Mutations


These mutations enhance specific weapon types, rewarding mastery with powerful bonuses.
  • Lil Fist
    • Unlock: Kill 40/100/200 creatures with bare hands.
    • Effect: Charge a powerful punch and deal heavy damage to insects.
  • Smasher
    • Unlock: Kill 40/100/200 creatures with clubs.
    • Effect: Adds a stun effect to club attacks, making it easier to stagger large enemies.
  • Javelineer
    • Unlock: Kill 40/100/200 creatures with spears.
    • Effect: Spear throws deal bonus damage, and some damage is reflected back to attackers.
  • Assassin
    • Unlock: Kill 40/100/200 creatures with daggers.
    • Effect: Increases critical hit chance on dash strikes; dual daggers deal extra critical damage.
  • Sharpshooter
    • Unlock: Kill 40/100/200 creatures with bows.
    • Effect: Charged bow shots have a higher critical hit chance.
  • Blademaster
    • Unlock: Kill 40/100/200 creatures with swords.
    • Effect: Sword hits reduce enemy damage against you but temporarily remove stamina on strike.
  • Whittle Wizard
    • Unlock: Kill 40/100/200 creatures with staves.
    • Effect: Boosts elemental staff attacks and increases crit chance against enemies with max status effects.

2. Combat Abilities Mutations


These mutations improve defensive and offensive techniques in battle.


  • Parry Master

    • Unlock: Perform 30/80/150 perfect parry blocks.
    • Effect: Perfect blocks restore stamina.
  • Frenzy

    • Unlock: Defeat the Mysterious Stranger (post-story).
    • Effect: Build rage on attacks; when enraged, gain bonus damage and health regeneration.
  • Guard Dog

    • Unlock: Complete 1/4/9 MIX.R events.
    • Effect: Deal increased damage to enemies raiding your base.

3. Exploration Mutations


These mutations help with traversal and discovering secrets.


  • Natural Explorer

    • Unlock: Discover 20/50/80 points of interest.
    • Effect: Increases sprint speed outside combat.
  • Trapper Peep.r

    • Unlock: Collect 25/50/75 Gold Cards.
    • Effect: Boosts critical hit damage.

4. Survival Mutations


These mutations improve stamina, revival speed, and resistance to hazards.


  • Cardio Fan

    • Unlock: Deplete stamina 100/250/500 times.
    • Effect: Faster stamina regeneration and reduced exhaustion time.
  • Reliable Fan

    • Unlock: Revive 5/15/30 allies.
    • Effect: Revive teammates and pets faster.
  • Fresh Defense

    • Unlock: Eat 1/5/10 Mint Shards.
    • Effect: Reduces sizzle burn rate and poison gas damage.
  • Spicy Safety

    • Unlock: Eat 1/5/10 Spicy Shards.
    • Effect: Grants resistance to chill, freeze, and reduces shatter damage.
  • Mithridatism

    • Unlock: Kill 5/50/150 venomous creatures.
    • Effect: Slows venom spread in your character.

How to Equip More Mutations in Grounded 2


Initially, you can only equip two mutations at a time. To unlock additional slots, invest Milk Molars into the Max Active Mutations perk under the Mutations menu.

Final Tips for Unlocking Mutations Faster


  • Focus on one weapon type to quickly unlock its related mutation.
  • Farm weaker enemies for kill-based mutations.
  • Explore thoroughly to unlock Natural Explorer faster.
  • Participate in MIX.R events to progress Guard Dog.


By strategically unlocking and equipping mutations, you’ll become a formidable survivor in Grounded 2. Which mutation will you unlock first?

Platform(s): Windows PC, Xbox Series X/S
Genre(s): Survival
Developer(s): Obsidian Entertainment , Eidos-Montréal
Publisher(s): Xbox Game Studios
Engine: Unreal Engine 5
Mode: Single-player, multiplayer
Video preview



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