Elden Ring Nightreign: How To Get Boluses

How To Get Boluses in Elden Ring Nightreign

By Daniel Hidalgo | 2025-06-05 11:44:20

Status ailments in Elden Ring Nightreign can be a major obstacle, but Boluses offer one of the most effective ways to counter them. These versatile consumables not only cure harmful effects but also provide powerful permanent buffs, making them essential for survival.
In this guide, we’ll cover how to find Boluses, their hidden mechanics, and how to use them strategically to gain lasting advantages in your playthrough.

How to Get Boluses in Elden Ring Nightreign

Unlike other consumables, Boluses can be acquired through multiple methods:

Breaking Crates & Jars – Smashing destructible objects may yield random Boluses, though this method isn’t reliable for farming.
Defeating Enemies – Some foes drop Boluses as loot, especially those associated with status effects (e.g., poison or rot enemies).
Opening Chests – Explore dungeons and hidden areas to find chests containing Boluses.
Merchant Purchases – Certain vendors sell Boluses, so check traders in different regions.

While these methods help stockpile Boluses, their true power lies in a recently discovered hidden mechanic.

Hidden Boluses Mechanic: Permanent Buffs Explained

Inventory space is limited in Elden Ring Nightreign, forcing players to prioritize consumables wisely. However, Boluses have a game-changing feature—many grant permanent buffs when used, even if you don’t need their status-curing effects.

How It Works

If you find a Bolus you can’t carry or won’t use later, consume it immediately. Most Boluses provide bonus resistances and gradual HP regeneration alongside their primary effect. These buffs persist for the entire playthrough, making them invaluable for long-term survival.

List of Boluses and Their Permanent Buffs

Bolus Type	Primary Effect	Permanent Buff
Thawfrost Bolus	Cures frostbite	Boosts frost resistance + HP regeneration
Stimulating Bolus	Removes sleep buildup	Increases sleep resistance + HP regen
Stanching Bolus	Prevents blood loss	Enhances bleed resistance + HP regen
Rejuvenating Bolus	Counters death blight	Improves death resistance + HP regen
Preserving Bolus	Cures scarlet rot	Strengthens rot resistance + HP regen
Neutralizing Bolus	Removes poison	Raises poison resistance + HP regen
Clarifying Bolus	Reduces madness buildup	Increases madness resistance + HP regen

By strategically using Boluses, you can stack multiple resistances and sustain passive HP recovery, significantly improving your survivability.

Best Strategies for Using Boluses

Use Spare Boluses Immediately – Don’t discard them; activate them for permanent stat boosts.

Prioritize High-Risk Areas – Before entering zones with heavy status effects (e.g., rot swamps orfrost dungeons), use the corresponding Bolus for extra resistance.

Combine with Other Buffs – Stack Bolus effects with armor, talismans, and spells for maximum resistance.

Farm When Necessary – If a particular Bolus is rare, revisit enemy spawns or merchants to stock up.

Final Thoughts

Boluses in Elden Ring Nightreign are more than just emergency cures—they’re a hidden progression system that rewards smart inventory management. By understanding theirpermanent buff mechanics, you can turn seemingly disposable items intolong-term advantages.

For more Elden Ring Nightreign tips, check out our guides on best builds, hidden locations, and boss strategies!

Platform(s): PlayStation 4 PS4, PlayStation 5 PS5, Windows PC, Xbox One, Xbox Series X/S

Genre(s): Action role-playing, roguelike

Developer(s): FromSoftware

Publisher(s): Bandai Namco Entertainment

Mode: Single-player, multiplayer

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